USP7: NOVEL DRUG TARGET IN CANCER THERAPY

USP7: Novel Drug Target in Cancer Therapy

Ubiquitin specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUB) that erases ubiquitin and protects substrate protein from degradation.Full activity of USP7 requires 2649-20 the C-terminal Ub-like domains fold back onto the catalytic domain, allowing the remodeling of the active site to a catalytically competent state by the C-term

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Secure Communication With Energy-Harvesting Buffer-Aided Jammer

Information security and self-sustainability are crucial to resource-limited wireless networks.In this paper, we assess the secrecy milwaukee 2485-22 performance of the legitimate link without having eavesdropper’s channel state information (CSI) while considering an energy harvesting (EH) jammer with finite and infinite energy buffer sizes.

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Suicides as a response to adverse market sentiment (1980-2016).

Financial crises inflict significant human as well as economic hardship.This paper focuses on the human fallout of capital market stress.Financial stress-induced behavioral changes can manifest in higher suicide and murder-suicide rates.We find that these rates also correlate with the Gross Domestic Product (GDP) growth rate (negatively associated;

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